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KMID : 0438219750120010365
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Korea University Medical Journal
1975 Volume.12 No. 1 p.365 ~ p.368
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On the Glitter Cell in Urinary Sediment
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Abstract
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The leucocyte arising from infectious renal disease tends to be swollen and show Brownian movement in the cytoplasm, which is so-called ´Glitter cell. ´
Of the various methods for staining urinary sediment the supravital staining with gentian violet and safranin o (Sternheimer-Malbin stain) was described to be most effective in discriminating Glitter cell from other polymorphonuclear cell.
With this stain, Glitter cell appears pale blue in contrast to the violet staining of other leucocytes. The granular motility and different nuclear absorption of dye is considered by the effect of nonsp-
ecific injury to the cells that decreased cytoplasmic viscosity and allowed Brownian movement of
granules.
By recent reports, Glitter cell is found not only in chronic pyelonephritis but also in lower urinary tract infection, therofore the specificity of Glitter cell is not authorized.
The urinary sediments of 68 cases with more than 3/HPF polymorphonuclear cells were stained with the mixture of gentian violet and safranin o solution.
The results were as follows:
1) Glitter cell is no longer specific in certain disease because it was found not only in chronic pyelonephritis but also in lower urinary tract infection and other diseases.
2) The incidence of Glitter cell was relatively high in low urine specific gravity.
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